13C Ubt Breath Test Kit

13C Ubt Breath Test Kit

13C ubt breath test kit The current non-invasive methods for diagnosing Hp mainly include urea breath test, stool antigen test and serological test. Routine serological tests to detect serum Hp antibody IgG, its positive is not necessarily the current infection, can not be used for...
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13C ubt breath test kit


The current non-invasive methods for diagnosing Hp mainly include urea breath test, stool antigen test and serological test. Routine serological tests to detect serum Hp antibody IgG, its positive is not necessarily the current infection, can not be used for re-examination after eradication therapy, so the clinical application is limited.


 Excluding serological tests, the only non-invasive diagnostic methods are urea breath test and stool antigen test. The sensitivity and specificity of the currently used monoclonal antibody stool antigen test to detect Hp is similar to that of the urea breath test, but the clinical application is not as widespread as the urea breath test. The reason may be that the application is not convenient and the promotion is not enough.


 The Maastricht-5 consensus proposed that the 13C-urea breath test is the best method for diagnosing Hp infection, with high sensitivity and specificity; the 14C-urea breath test is also recommended because it is cheap, but it is radioactive and cannot be used in children and Pregnant women. Therefore, the urea breath test is currently the most widely used clinically and relatively accurate detection method, which means that it can be called the "gold standard" for non-invasive diagnosis of Hp infection.


In a verification study reported in South Korea, the false positive rate of detection according to the threshold set by the reagent (without citric acid) provider reached about 30%, which greatly affected the credibility of the urea breath test as the "gold standard" .


Richen 13C urea breath test has acidified formula increases H.pylori urease activity, inhibits non-H.pylori urease activity, slows gastric emptying, makes 13C urea fully contact H.pylori, and overcomes the focal distribution of H.pylori, improve the accuracy of detection.


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